Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11842874
rs11842874
MCF2L
A 0.810 GeneticVariation GWASDB Through large-scale replication, we establish a robust association with SNPs in MCF2L (rs11842874, combined odds ratio [95% confidence interval] 1.17 [1.11-1.23], p = 2.1 × 10(-8)) across a total of 19,041 OA cases and 24,504 controls of European descent. 21871595

2011
dbSNP: rs12982744
rs12982744
DOT1L
G 0.810 GeneticVariation GWASDB Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. 22566624

2012
dbSNP: rs3815148
rs3815148
COG5
C 0.810 GeneticVariation GWASDB The C allele of rs3815148 on chromosome 7q22 (minor allele frequency 23%; intron 12 of the COG5 gene) was associated with a 1.14-fold increased risk (95% confidence interval 1.09-1.19) of knee and/or hand OA (P = 8 x 10(-8)) and also with a 30% increased risk of knee OA progression (95% confidence interval 1.03-1.64) (P = 0.03). 20112360

2010
dbSNP: rs4730250
rs4730250
DUS4L
G 0.810 GeneticVariation GWASDB With a cumulative sample size of 6709 cases and 44 439 controls, one genome-wide significant locus was identified on chromosome 7q22 for knee OA (rs4730250, p=9.2 × 10⁻⁹), thereby confirming its role as a susceptibility locus for OA. 21068099

2011
dbSNP: rs10948172
rs10948172
SUPT3H ; LOC101929770
G 0.800 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs11177
rs11177
GNL3 ; PBRM1 ; SNORD19 ; SNORD136
A 0.800 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1417066
rs1417066
LYPLAL1-AS1 ; LOC107985272
G 0.800 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs10492367
rs10492367 		0.710 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs10172410
rs10172410
ITGA4
0.700 GeneticVariation GWASDB A variant in MCF2L is associated with osteoarthritis. 21871595

2011
dbSNP: rs1034762
rs1034762
COL2A1
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs10948155
rs10948155 		0.700 GeneticVariation GWASDB Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. 22566624

2012
dbSNP: rs11107957
rs11107957
NAV3
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs12618428
rs12618428 		0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs12901404
rs12901404
RYR3
0.700 GeneticVariation GWASDB A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium. 19508968

2009
dbSNP: rs12923310
rs12923310 		0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1355782
rs1355782
CPNE4
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1404866
rs1404866
LOC102724680
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1566347
rs1566347
SORBS2
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1627411
rs1627411 		0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs17578878
rs17578878
TBC1D1
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1876836
rs1876836
MFHAS1
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs1998094
rs1998094
LINC02319
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs2626053
rs2626053
UNC5C
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs2966417
rs2966417
LOC105375451
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012
dbSNP: rs2979715
rs2979715
STMN2
0.700 GeneticVariation GWASDB Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. 22763110

2012